Anti-Tumor Cell Therapy
A full-spectrum, integrative approach to cancer care can be achieved through the use of anti-tumor cellular therapy in conjunction with other forms of cancer therapy, resulting in non-traditional approaches to cancer treatment that consider the needs of the patient as a whole as well as the disease itself.
The objective of cellular immunotherapy is to reactivate and potentiate the activity of lymphocyte cells, which are suppressed in cancer patients.
In this way, it is intended to restore the antitumor response and suppress the progression of the disease in the body.
-Lymphoid cell therapy.
(CD4+ Lymphocytes, CD 8+ Lymphocytes and NK Cells)
Normal Immune Response
The ability of our immune system to contain and eliminate cancer cells depends on the proper activation and coordination of the white blood cells in our body. The group of cells responsible for activating an immune response in our bodies are the white blood cells.
There is a wide variety of specialized white blood cells with specific functions necessary for the body to protect itself from diseases such as infections or cancer.
Some of these cells that are vital for the production of an immune response are:
- CD4+ T Lymphocyte
It is one of the most active lymphocytes in the immune response, its functions are directly related to the production of antibodies by stimulating B Lymphocytes, as well as in the activation and production of cytotoxic cells such as Natural Killer cells, or phagocytic cells such as Macrophages. If there is an inactivation or lack of this type of cells in the patient, it can lead to an immune compromise that can be fatal, as occurs in patients with HIV or cancer.
- CD8+ Lymphocyte
It is a lymphocyte with cytotoxic function with important activity regulating and annihilating abnormal cells in our body, such as virus infected cells or tumor cells. By recognizing some of these abnormal cells through membrane receptors, it releases cytotoxins such as perforins that damage the cell membrane, as well as cytokines such as Tumor Necrosis Factor (TNF) or Gamma Interferon (IFN-γ) with antitumor effects.
- Natural Killer Cells Activators
They are a type of lymphocyte with the ability to recognize and destroy tumor or virus-infected cells directly, without prior sensitization by antibodies. This ability to trigger their cytotoxic effects by direct recognition makes them a great tool of the innate immune system and an important defense against the development of cancer.
- Dendritic Cells
Dendritic cells (DCs) play a critical role in regulating the immune response. They are the main antigen-presenting cells, because of their ability to capture, process and present antigens optimally to T lymphocytes, and generate specific immune responses. In this way the formation of antibodies concentrates the immune system’s attack on infected cells or tumor cells.
Currently, the ability to cultivate, mature and activate this type of immune cells in the laboratory, has generated a new approach in the treatment against diseases such as cancer or HIV, where the immune system is compromised by the effects of the disease.
At Omsana Health, we implement these therapies by taking a blood sample from the patient of approximately 300 ml, sending it to a specialized laboratory where the processes of cell duplication, maturation and activation are performed, and then transfused to the patients.
Lymphoid cell therapy (CD4+ T lymphocyte, CD8+ T lymphocyte and Natural Killer cells)
The objective of lymphoid cell therapy is to increase the number of active lymphocyte cells in the body.
This is done through the culture, maturation and activation of cell lines; CD4+ Lymphocytes, CD8+ T Lymphocytes and Natural killer cells, in this way we amplify the immune response against cancer cells.
Dendritic Cell (DC) Therapy
Dendritic cell therapy consists of taking a blood sample from the patient to obtain immature dendritic cells and through a biochemical process we stimulate their maturation and activation, so that once they are transfused to the patient they can help in the immune response against cancer.
Lymphokine-activated killer cell (LAK) therapy
Lymphokine-activated killer cells, also known as LAK cells. Playing an integral role in the body’s defenses, incubation of lymphocytes in culture media rich in interleukin-2 (IL-2) results in the development of lytic activity against autologous and allogeneic tumor cells.